Juvederm Volbella, Restylane Silk and Restylane Refyne are the "finest" of the hylauronic acid gels and are designed for filling finer lines and for subtle lip enhancement, with results lasting 6-12 months
Juvderm Ultra XC, Ultra Plus, Vollure and Restylane-L and Defyne are used for injection into the lips, nasolabial folds, marionette lines, as well as generalized volume loss in the cheeks, and jawline. These formulations help smooth moderate to severe facial wrinkles and folds with results lasting 9-18 months.
Juvederm Voluma and Restylane Lyft are considered to be more "robust" versions of hylauronic acid gel. These gels are designed to contour and add fullness to the cheeks and midface regions, which helps correct age related volume loss, with results lasting 12-24 months.